1-Hydroxy-7-azabenzotriazole (HOAt) and N-[(dimethylamino)-1H-1,2,3-triazolo-[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate N-oxide (HATU)
نویسندگان
چکیده
منابع مشابه
Chemistry of Peptide Materials
Aib α-Aminoisobutyric acid or Cα-methylalanine (αMe)Phe Cα-methylphenylalanine (αMe)Val Cα-methylvaline BOP (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium CIP 2-Chloro-1,3-dimethylimidazolidium phosphate Db z g Cα,α-dibenzylglycine Deg Cα,α-diethylglycine Dφg Cα,α-diphenylglycine Dp n g Cα,α-di-n-propylglycine EDC 1-(3-Dimethylamino)propyl-3-ethylcarbodiimide HATU 2-(1H-7-aza-1,2,3-benzot...
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The cyclic depsipeptides, AM-toxins I and II and AM-toxin I analogs, were efficiently and rapidly prepared by the Fmoc-based solid-phase method for the synthesis of linear depsipeptides, with N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide (HATU) being used for their subsequent cyclization.
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An ab initio study has been performed for the electronic, spectroscopic, and chemical properties of the most stable configuration of the (CdO)n nanoclusters by employing B3LYP-DFT/LanL2DZ method. Different isomers were optimized to obtain structural stability and numerous chemical parameters such as dipole moment, ionization potential, etc. We report here the vibrational frequencies of the most...
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We describe a new 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxide hexafluorophosphate (HATU)-mediated coupling reaction to produce 2-imino benzo[e]-1,3-oxazin-4-ones from salicylic acids and anilines. Mechanistic studies support a reaction pathway in which HATU mediates carbon transfer to the initially formed salicylanilides to form in succession reactive tetramethyli...
متن کاملN-[7-Ethoxy-1-(prop-2-en-1-yl)-1H-indazol-4-yl]-4-methylbenzenesulfonamide
In the title compound, C(19)H(21)N(3)O(3)S, the C-SO(2)-NH-C torsion angle is 103.72 (11)°. The almost planar indazole ring [r.m.s. deviation = 0.0202 (14) Å] is twisted away from the methyl-benzene ring by 76.87 (7)°. The vinyl group is disordered over two orientations with site occupancies of 0.622 (10) and 0.378 (10). The S atom has a distorted tetra-hedral geometry [maximum deviation: O-S-O...
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ژورنال
عنوان ژورنال: Synlett
سال: 2001
ISSN: 0936-5214,1437-2096
DOI: 10.1055/s-2001-18098